Doç. Dr.

Sinan Tanyolaç

Bilimsel Yayınlar

Uluslararası Hakemli Dergilerde Yayınlanan Makaleler

Uluslararası hakemli dergilerde yayınlanan makaleler (SCI & SSCI & Arts and Humanities)

Exocrine Pancreatic Insufficiency in Diabetes: Association with Cardiovascular Disease and Insulin Therapy. Balamir M, Tanyolaç S, et al. J Clin Med. 2026;15(4):1023. doi: 10.3390/jcm15041023.

Insulin Resistance and Cancer: In Search for a Causal Link. Chiefari E, Tanyolaç S, et al. Int J Mol Sci. 2021 Oct 15;22(20):11137. doi: 10.3390/ijms222011137.

Long-Term Effectiveness of Liraglutide for Weight Management and Glycemic Control in Type 2 Diabetes. Mirabelli M, Chiefari E, Caroleo P, Arcidiacono B, Corigliano DM, Giuliano S, Brunetti FS, Tanyolaç S, Foti DP, Puccio L, Brunetti A. Int J Environ Res Public Health. 2019 Dec 27;17(1):207. doi: 10.3390/ijerph17010207.

Evidence that an HMGA1 gene variant associates with type 2 diabetes, BMI, and HDL cholesterol in a Hispanic-American population. Pullinger CR, Goldfine ID, Tanyolac S, et.al. Metab Syndr Relat Disord. 2014;12(1):25-30. doi: 10.1089/met.2013.0086.

A polymorphism of HMGA1 is associated with increased risk of metabolic syndrome and related components. Chiefari E, Tanyolaç S, Iiritano S, et.al. Sci Rep. 2013;20(3):1491.

Comment on: Marquez et al. Low-frequency variants in HMGA1 are not associated with type 2 diabetes risk. Diabetes 2012;61:524-530. Brunetti A, Chiefari E, Pullinger CR, Tanyolac S, Foti D, Durlach V, Goldfine ID. Diabetes. 2012 May;61(5):e3. doi: 10.2337/db12-0051.

Bonnefond A, Lomberk G, Buttar N, Busiah K, Vaillant E, Lobbens S, Yengo L, Dechaume A, Mignot B, Simon A, Scharfmann R, Neve B, Tanyolaç S, Hodoglugil U, Pattou F, Cavé H, Iovanna J, Stein R, Polak M, Vaxillaire M, Froguel P, Urrutia R. "Disruption of a novel Kruppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus." J Biol Chem. 2011 Aug 12;286(32):28414-24.

Brunetti A, Chiefari E, Pullinger CR, Tanyolac S, Foti D, Durlach V, Goldfine ID. "Low Frequency Variants in HMGA1 are associated with Type 2 Diabetes." Diabetes. 2012 May;61(5):e3.

Chiefari E, Tanyolaç S, Paonessa F, Pullinger CR, Capula C, Iiritano S, Mazza T, Forlin M, Fusco A, Durlach V, Durlach A, Malloy MJ, Kane JP, Heiner SW, Filocamo M, Foti DP, Goldfine ID, Brunetti A. "Functional variants of the HMGA1 gene and type 2 diabetes mellitus." JAMA. 2011 Mar;305(9):903-912.

Tanyolaç S, Bremer AA, Hodoglugil U, Movsesyan I, Pullinger CR, Heiner SW, Malloy MJ, Kane JP, Goldfine ID. "Genetic Variants of the ENPP1/PC-1 Gene Are Associated with Hypertriglyceridemia in Male Subjects." Metab Syndr Relat Disord. 2009 Dec;7(6):543-8.

Kurtoglu S, Atabek ME, Dizdarer C, Pirgon O, Isguven P, Emek S; PREDICTIVE Turkey Study Group. "Insulin detemir improves glycemic control and reduces hypoglycemia in children with type 1 diabetes: findings from the Turkish cohort of the PREDICTIVE observational study." Pediatr Diabetes. 2009 Sep;10(6):401-7.

Tanyolaç S, Mahley RW, Hodoglugil U, Goldfine ID. "Gender differences in the relationship of ENPP1/PC-1 variants to obesity in a Turkish population." Obesity (Silver Spring). 2008 Nov;16(11):2468-71.

Tanyolaç S, Sertkaya Cikim A, Doğan Azezli A, Orhan Y. "Correlation between educational status and cardiovascular risk factors in an overweight and obese Turkish female population." Anadolu Kardiyol Derg. 2008 Oct;8(5):336-41.

Tanyolaç S, Cikim Sertkaya A, Azezli AD, Orhan Y. The alarm and action levels of waist circumference in overweight and obese Turkish women. Obesity Research & Clinical Practice. 2007 Dec;4(1):253-259.

Ozbey N, Sencer A, Tanyolac S, Kurt R, Sencer S, Bilgic B, Turantan I, Molvalilar S. "An intrasellar germinoma with normal cerebrospinal fluid beta-HCG concentrations misdiagnosed as hypophysitis." Hormones (Athens). 2006 Jan-Mar;5(1):66-70.

Hodoglugil U, Tanyolaç S, Williamson DW, Huang Y, Mahley RW. "Apolipoprotein A-V: a potential modulator of plasma triglyceride levels in Turks." J Lipid Res. 2006 Jan;47(1):144-53.

İdari Görevler

T.C. Sağlık Bakanlığı İstanbul Kanuni Sultan Süleyman Eğitim Araştırma Hastanesi İç Hastalıkları Eğitim Sorumlusu, 2015

Patentler

Brunetti A, Chiefari E.D., Foti D, Paonessa F, Iiritano S, Goldfine I.D., Kane J.P., Malloy M, Pullinger C, Tanyolac S. "POLIMORFISMO DEL GENE HMGA1, METODO DI INDIVIDUAZIONE E METODO DI DIAGNOSI GENETICA DI INSULINO-RESISTENZA E/O DIABETE MELLITO DI TIPO 2". Catanzaro, Italy, patent no: CZ2009A000009, 06/06/2009.

Brunetti A, Chiefari E.D., Foti D, Paonessa F, Iiritano S, Goldfine I.D., Kane J.P., Malloy M, Pullinger C, Tanyolac S. "GENETİC MUTATIONS PREDICTIVE OF TYPE 2 DIABETES". University of California San Francisco, California, USA, docket no: UCSF-412. Serial number: P-116454. License number: 542147

Ödüller

Functional variants of the HMGA1 gene cause a major decrease in Insulin receptor expression adlı çalışma ile 7th Annual World Congress on Insulin Resistance, November 2009, San Francisco, USA. En iyi araştırmacı ödülü.

Üye Olunan Dernekler

The Endocrine Society

American Association of Clinical Endocrinologists

American Diabetes Association

Türkiye Endokrinoloji ve Metabolizma Derneği (TEMD)

Türk İç Hastalıkları Uzmanlık Derneği

Türkiye Obezite Derneği