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Prof. Dr. Sarhan Sakarya

Ad Soyad
Sarhan Sakarya
Unvan
Prof. Dr.
Tıbbi Birim
Enfeksiyon Hastalıkları
Şube
MEDICANA INTERNATIONAL İZMİR, HİZMETİNİZDE!
Telefon
0232 970 35 35
E-Posta
sarhan.sakarya@medicana.com.tr
E-RANDEVU
Mezun Olduğu Tıp Fakültesi ve Yılı
G.A.T.A TIP FAKÜLTESİ
Uzmanlık Eğitimi Aldığı Yer ve Yılı
G.A.T.A TIP FAKÜLTESİ
Mesleki Deneyim
2015-Adnan Menderes Üniversitesi Tıp Fakültesi Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim dalı Klinik Mikrobiyoloji Laboratuvar Sorumlusu
2004- Adnan Menderes Üniversitesi Eğitim ve Araştırma Hastanesi Enfeksiyon Kontrol Komite Başkanlığı
200-Adnan Menderes Üniversitesi Tıp Fakültesi Enfeksiyon Hastalıkları ve Klinik mikrobiyoloji Anabilim dalı Öğretim Üyesi
2002-2012Adnan Menderes Üniversitesi Bilimsel Araştırma ve Uygulama Merkez Müdürlüğü
2000-2015 Adnan Menderes Üniversitesi Tıp Fakültesi Enfeksiyon Hastalıkları ve Klinik mikrobiyoloji Anabilim Dalı Başkanı
1996-1999 University of Maryland –ABD Araştırmacı (Visiting Scientist), Endotel-Nötrofil Laboratuvarı Proje Sorumlusu.
1993-1996 Enfeksiyon Hastalıkları Klinik Sorumlusu, 600 Yataklı Mareşal Çakmak Askeri Hastanesi, Erzurum
1986-1989Revir Baştabibi, 6. Piyade Tümeni, İstanbul
Tıbbi İlgi Alanları
İnsan Endotel Hücresi Ekim ve Üretimi Teknikleri
Hücre Transformasyon Teknikleri
Hücre Transfeksiyonu Teknikleri
İnsan Lökosit Ayrım Teknikleri
Invitro Adhezyon, Kemotaksis, Transendoteliyal Migrasyon
Western Blot Tekniği
Immün Presipitasyon Teknikleri
Floresein Mikroskopi Teknikleri
Immün Floresan Teknikleri
Radyoimmünessay
Polimeraz Zincir Reaksiyon (PCR)
Enzimimmünessay
Hücre Biyokimyası Teknikleri
Özellikli İşlem

Bilimsel Yayınlar
Makaleler
A-Uluslar arası
1.I. Yildiz, O. Yilmaz , E. Tileklioglu, S. Sakarya, H. Ertabaklar, Stabilised Hypochlorous Acıd: A New Therapeutic Strategy Agaınst Dangerous Parasitic Eye Infection Agent Acanthamoeba spp. Journal of Environmental Protection and Ecology 19, No 3, 1397–1404 (2018)
2.Yılmaz, Ö., Sakarya. S., Is ‘Hanging Drop’ a Useful Method to Form Spheroids of Jimt, Mcf-7, T-47d, Bt-474 That are Breast Cancer Cell Lines Single Cell Biol, 7, No 1 (2018)
3.Uğur Avcıbaşı, Hasan Demiroğlu, Serhan Sakarya, Perihan Unak, Volkan Tekin, Buket Ates¸ The effect of radiolabeled antibiotics on biofilm and microorganism within biofilm, Journal of Radioanalytical and Nuclear Chemistry 2018 316:275–287
4.Ertugrul BM, Lipsky BA, Guvenc U; Turkish Intralesional Epidermal Growth Factor Study Group for Diabetic Foot Wounds. An Assessment of Intralesional Epidermal Growth Factor for Treating Diabetic Foot Wounds. The First Experiences in Turkey. J Am Podiatr Med Assoc. 2017 Jan;107(1):17-29. doi: 10.7547/15-056
5.Wilcox MH, Gerding DN, Poxton IR, Kelly C, Nathan R, Birch T, Cornely OA, Rahav G, Bouza E, Lee C, Jenkin G, Jensen W, Kim YS, Yoshida J, Gabryelski L, Pedley A, Eves K, Tipping R, Guris D, Kartsonis N, Dorr MB; MODIFY I and MODIFY II Investigators. Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection. N Engl J Med. 2017 Jan 26;376(4):305-317. doi: 10.1056/NEJMoa1602615.
6.Ozturk B, Gunay N, Ertugrul BM, Sakarya S Effects of vancomycin, daptomycin, and tigecycline on coagulase-negative staphylococcus biofilm and bacterial viability within biofilm: an in vitro biofilm model. Can J Microbiol. 2016 Sep;62(9):735-43. doi: 10.1139/cjm-2015-0855.
7.Sakarya, S., Gunay, N., Karakulak, M., Ozturk, B., Ertugrul, B., Hypochlorous Acid: An Ideal Wound Care Agent With Powerful Microbicidal, Antibiofilm, and Wound Healing Potency, Wounds, 2014, 26 (12), 342-350
8.Akca O., Unak P., Medine, E.I., Sakarya S., Kilcar A.Y., Ichedef C., Bekis R., Timur S., Radioiodine labeled CdSe/CdS quantum dots: Lectin targeted dual probes. Radıochımıca Acta, 2014, 102, (9), 849-60
9.Sakarya S, Gunay N, Saccharomyces boulardii expresses neuraminidase activity selective for α2,3-linked sialic acid that decreases Helicobacter pylori adhesion to host cells. APMIS. 2014 122(10):941-50
10.Kara A, Unak P, Selcuki C, Akca O, Medine E.I., Sakarya S. PHA-L lectin and carbohydrate relationship: conjugation with CdSe/CdS nanoparticles, radiolabeling and in vitro affinities on MCF-7 cells. J Radioanal Nucl Chem (2014), 299:1, 807-813
11.Ozkaya F., Unak P., Medine E.I., Sakarya S., Unak G.,Timur S. 18FDG conjugated magnetic nanoparticle probes: synthesisand in vitro investigations on MCF-7 breast cancer cells. J Radioanal Nucl Chem (2013) 295:1789–1796
12.Yilmaz T, Unak P, Biber Muftuler F.Z, Medine E.I, Sakarya S, Ichedef C.A. Unak T. Diethylstilbestrol glucuronide (DESG): synthesis, labeling with radioiodine and in vivo/in vitro evaluations. J Radioanal Nucl Chem (2013) 295:1395–1404
13.Ediz M, Avcıbaşı U, Unak P, Müftüler FZ, Medine EI, Yurt Kılçar A, Demiroğlu H, Gümüşer FG, Sakarya S. Investigation of Therapeutic Efficiency of Bleomycin and Bleomycin-Glucuronide Labeled with (131)I on the Cancer Cell Lines. Cancer Biother Radiopharm. 2013 ;28(4):310-9
14.Öncü S, Saylak Ö, Köseoğlu K, Öztürk B, Eşiyok A, Çörekli E, Sakarya S. Renal cyst infection caused by Brucella abortus.Ren Fail. 2013;35(2):302-4
15.Yuksel M, Colak DG, Akin M, Cianga I, Kukut M, Medine EI, Can M, Sakarya S, Unak P, Timur S, Yagci Y., Nonionic, Water Self-Dispersible "Hairy-Rod" Poly(p-phenylene)-g-poly(ethylene glycol) Copolymer/Carbon Nanotube Conjugates for Targeted Cell Imaging. Biomacromolecules. 2012, 13 (9), pp 2680–2691
16.Cekic B, Muftuler FZ, Kilcar AY, Gunay N, Sakarya S, Unak P., Anti toxic effect of broccoli extract on stannous dichloride toxicity.Acta Cir Bras. 9:606-10. 2012
17.Demiroğlu H, Avcıbaşı U, Unak P, Müftüler FZ, Ichedef CA, Gümüşer FG, Sakarya S., Radiolabeling of Bleomycin-Glucuronide with (131)I and Biodistribution Studies Using Xenograft Model of Human Colon Tumor in Balb/C Mice, Cancer biother Radiopharm. 27(6):371-83 2012
18.Colak D.G, Cianga I, Demirkol D.O, Kozgus O, Medine E.I, Sakarya S, Unak P, Timur S, Yagci Y,The synthesis and targeting of PPP-type copolymers to breast cancer cells: Multifunctional platforms for imaging and diagnosis. J. Mater. Chem., 2012, 22, 9293-9300
19.Unak, P; Guldu, OK; Medine, EM; Muftuler, FZB; Sakarya, SM; Timur, SF, Radiolabeling of Magnetic Nanoparticles Conjugated Moxifloxacin (MOX) and Investigation of In Vitro Biological Affinities, European Journal of Nuclear Medıcıne and Molecular Imagıng, 39 Supplement: 2 Pages: S535-S535 Meeting Abstract: P0817 Published: OCT 2012
20.Ertugrul BM, Gencer P, Ozturk B, Saylak Ersoy OM, Sakarya S, Adult-onset Still's disease in an 83-year-old. J Am Geriatr Soc. 2012 Jan;60(1):162-4.
21.Ertugrul BM, Uyar G, Ozturk B, Sakarya S, A Rare Presentation of Endocarditis in Adult-onset Still's Disease in Diagnosis of Fever of Unknown Origin. J Rheumatol. 2012 Jan;39(1):198-9.
22.Ertugrul B., Kırdar S., Saylak Ersoy O., Ture M., Erol N., Ozturk B., Sakarya S.; The Seroprevalance of Crimean-Congo hemorrhacig fever among inhabitants living in the endemic regions of Western Anatolia; Scandinavian Journal of Infectious Diseases, 2012, 44 (4): 276-81
23.Unak G., Ozkaya F., Medine E.I., Kozgus O., Sakarya S., Bekis R, Unak P.,Timur S., Gold nanoparticle probes: Design and in vitro applications in cancer cell culture; Colloids and Surfaces B: Biointerfaces, 2012, 90, 217- 226
24.Ertuğrul BM, Erol N, Ozturk B, Saylak OM, Cetin K, Sakarya S., Food-born Tonsylopharangitis outbreak in a hospital cafetaria; 2012, 40 (1);49-55
25.Akça Ö., Ünak P., Medine E.I., Özdemir Ç, Sakarya S., Timur S., Fluorescein isothiocyanate labeled, magnetic nanoparticles conjugated D-penicillamine-anti-metadherin and in vitro. Revista Brasileira de Física Médica.2011;5(1):99-104
26.E.İlker Medine, Perihan Ünak, Serhan Sakarya, Feriha Toksöz, Investigation of In Vitro Efficiency of Magnetic Nanoparticle Conjugated 125I-Uracil Glucuronides On Adenocarcinoma Cells, Journal of Nanoparticle Research, 13, 4703-4715, 2011,
27.Dizman C, Demirkol DO, Ates S, Torun L, Sakarya S, Timur S, Yagci Y. Photochemically prepared polysulfone/poly(ethylene glycol) amphiphilic networks and their biomolecule adsorption properties. Colloids Surf B Biointerfaces. 2011; 88(1):265-70
28.Karadag M, Yilmaz G, Toiserkani H, Demirkol DO, Sakarya S, Torun L, Timur S, Yagci Y. Polysulfone/Pyrene membranes: a new microwell assay platform for bioapplications. Macromol Biosci. 2011;11(9):1235-43.
29.Yilmaz G, Toiserkani H., Demirkol D.O., Sakarya S., Timur S, Torun L., Yagci., Polysulfone based amphiphilic graft copolymers by click chemistry as bioinert membranes. Materials Science and Engineering C 31 (2011) 1091–1097
30.Yilmaz E, Savk E, Oncu S, Gulec GU, Ertugrul B, Sakarya S, Uslu M, Karaman G, Sendur N, Green staining of clothing: a signal for pseudomonal infection. Cutis. 2010 Dec;86(6):305-8.
31.Yılmaz G, Toiserkani H., Demirkol D.O, Sakarya S, Timur S, Yağcı Y., Torun L., Modification of Polysulfones by Click Chemistry: Amphiphilic Graft Copolymers and Their Protein Adsorption and Cell Adhesion Properties Journal of Polymer Science: Part A: Polymer Chemistry, 2011 Vol. 49, 110–117
32.Medine IE, Unak P, Sakarya S, Toksöz F, Enzymatic synthesis of uracil glucuronide, labeling with 125/131I, and in vitro evaluation on adenocarcinoma cells. Cancer Biother Radiopharm. 2010 Jun;25(3):335-44
33.Muftuler FZ, Unak P, Yolcular S, Kilcar AY, Ichedef C, Enginar H, Sakarya S., Synthesis, radiolabeling and In Vivo tissue distribution of an anti-oestrogen glucuronide compound, (99m)Tc-TOR-G. Anticancer Res. 2010 Apr;30 (4):1243-9.
34.Medine EI, Odaci D, Gacal BN, Gacal B, Sakarya S, Unak P, Timur S, Yagci Y. A New Approach for in vitro Imaging of Breast Cancer Cells by Anti-Metadherin Targeted PVA-Pyrene. Macromol Biosci. 2010 Jun 11;10(6):657-63.
35.Sakarya S, Göktürk C, Oztürk T, Ertugrul MB. Sialic acid is required for nonspecific adherence of Salmonella enterica ssp. enterica serovar Typhi
on Caco-2 cells. FEMS Immunol Med Microbiol. 58 (2010) 330–335
36.Sakarya S, Ertugrul MB, Oztürk T, Gökbulut C Effect of pharynx epithelial cells surface desialylation on receptor-mediated adherence of Staphylococcus aureus. J Appl Microbiol. 108 (2010) 1313–1322
37.Ertugrul B, Uyar Y, Yavas K, Turan C, Oncu S, Saylak O, Carhan A, Ozturk B, Erol N, Sakarya S. An outbreak of Crimean-Congo hemorrhagic fever in western Anatolia, Turkey.Int J Infect Dis. 2009, 13(6), e431-436
38.Ertugrul BM, Savk O, Ozturk B, Cobanoglu M, Oncu S, Sakarya S.The diagnosis of diabetic foot osteomyelitis: Examination findings and laboratory values. Med Sci Monit. 2009 Jun;15(6):CR307-312.
39.Turgut M, Ozsunar Y, Oncü S, Akyüz O, Ertuğrul MB, Tekin C, Gültekin B, Sakarya S.Invasive fungal granuloma of the brain caused by Aspergillus fumigatus: a case report and review of the literatureSurg Neurol. 2008 Feb;69(2):169-174
40.Sacar M, Onem G, Baltalarli A, Sacar S, Turgut H, Goksin I, Ozcan V, Sakarya S. Neuraminidase produces a decrease of adherence of slime-forming Staphylococcus aureus to gelatin-impregnated polyester fiber graft fabric: an experimental study. J Artif Organs. 2007; 10(3): 177-80.
41.Onem G, Sacar M, Sacar S, Sakarya S, Turgut H, Ozcan AV, Baltalarli A. “Neuraminidase decreases in vitro adherence of slime-forming coagulase-negative staphylococci to biosynthetic ovine collagen vascular graft”. Adv Ther. 23(2):256-62 (2006)
42.Oncu, S., Oncu, S., Okyay, P., Ertug, S. ve Sakarya, S. “Incidence and Risk Factors of HEV Infection in Pregnant Women” Med Sci Monit 12 (1): CR36-39 (2006)
43.Oncu S, Sakarya S. “Comparison of different dosages of vancomycin and teicoplanin in catheters infected with Staphylococcus epidermidis: An in-vitro antibiotic lock study” Current Theraupetic Research, 66 (4) 364-374 (2005)
44.Oncu S, Oncu S, ve S.Sakarya “Hepatitis A and B seropositivity among medical students” Health Policy 74 39–45 (2005)
45.Oncu, S., Oncu, S., Ozturk, B., Kurt, I., ve S. Sakarya “Elimination of Intraluminal Colonization by Antibiotic Lock in Catheters” Tohoku Journal of Experimental Medicine. 203 (1), May 1-8 (2004)
46.Sakarya, S., Oncu, S., Oncu, S., Ozturk, B., Tuncer, G., ve C. Sari “Neuraminidase produces dose-dependent decrease of slime production and adherence of slime-forming coagulase-negative staphylococci” Archives of Medical Research,35 (4) 275-278 (2004)
47.Sakarya, S., Oncu, S., Ozturk, B., ve S. Oncu, “Effect of preventive applications on prevalence of HBV and HCV infections in west Turkey” Saudi Medical Journal. 25 (8) Augst, 1070-1072, (2004)
48.Sakarya S, Rifat S, Zhou J, Bannerman DD, Stamatos NM, Cross AS, Goldblum SE. “Mobilization of neutrophil sialidase activity desialylates the pulmonary vascular endothelial surface and increases resting neutrophil adhesion to and migration across the endothelium” Glycobiology. 14 (6), 481-494 (2004)
49.Oncu S, Oncu S, Sakarya S. Anthrax - an overview. Med Sci Monit. 2003 Nov;9(11):RA276-83.
50.Öncü,S., ve S.Sakarya. “Central venous catheter-related infections: An overview with special emphasis on diagnosis,prevention and manegement,”The Internet Journal of Anesthesiology. 7, 1-14 (2003)
Sakarya, S., Ertem, G.T., Oncu, S., Kocak, I,

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